Hemorrhage and clinical implications SlideShare

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Anacare soothes ALL symptoms associated with piles. Anacare soothes ALL symptoms associated with hemorrhoids CLINICAL FEATURES Pallor, thirsty, cyanosis Tachycardia, tachypnoea Cold clammy skin due to vasoconstriction Dry face, dry mouth and goose skin appearance (due to contraction of arrector pilorum). Rapid thready pulse, hypotension Oliguria Features related to specific causes 17 Obstetric hemorrhage: anesthetic implications and management ACOG2018, NHS2019, Poonam S. Ghodki*, Shalini P. Sardesai 2014 Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising Hemorrhage generally indicates extravasation of blood due to vessel rupture. As described previously, capillary bleeding can occur under conditions of chronic congestion, and an increased tendency to hemorrhage from usually insignificant injury is seen in a wide variety of clinical disorders collectively called hemorrhagic diatheses ( Chapter 13 ) 2. Hemorrhage • Hemorrhage - Abnormal internal or external loss of blood. 3. Hemorrhage Classification. 4. External Hemorrhage • Results from soft tissue injury. • The seriousness of the injury is dependent on: - Anatomical source of the hemorrhage (arterial, venous, capillary) - Degree of vascular disruption - Amount of blood.

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The clinical presentation is generally that of an abrupt onset of a focal neurologic deficit that typically worsens steadily over 30 to 90 min. The common clinical presentations are shown in Table 366-6 . The putamen is the most common site for hypertensive hemorrhage , and the adjacent internal capsule is invariably damaged 22. CONCLUSION• Postpartum hemorrhage is still one of the leading causes of maternal near miss & maternal mortality in Sudan.•. Sudanese women are at higher risk for postpartum hemorrhage due to many social determinants.•. There are no standard guidelines for prevention and treatment for PPH in Sudan. 23 LOWERING ICP • Intravenous mannitol is the treatment of choice to lower increased intracranial pressure, effectively lowering ICP and benefiting brain metabolism [1]. • It is administered as an initial bolus of 1 g/kg, followed by infusions of 0.25 to 0.5 g/kg every six hours Clinical features • Usually mild and include mucosal bleeding, • soft tissue hemorrhage, menorrhagia in women, and hemarthrosis. 129. Laboratory findings • Clotting time- usually normal, may be slightly prolonged • Bleeding time- shows variation • Prothrombin time- normal • Tourniquet test- positive Treatment • Transfusion of.

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It is the second-most common form of hemophilia, rarer than haemophilia A. The genetic background, factor levels, and clinical symptoms are similar to those in hemophilia A. Factor IX deficiency leads to an increased propensity for hemorrhage. This is in response to mild trauma or even spontaneously, such as in joints or muscles External bleeding occurs from a body orifice or a traumatic wound. Internal bleeding requires a high level of clinical suspicion obtained through a thorough history and physical, laboratory tests, imaging, and close monitoring of vital signs. Hemorrhage is a leading cause of potentially preventable death, especially in the acute trauma population N. Díaz Villarroel. bstract Spontaneous abdominal hemorrhage is defined as intra-abdominal hemorrhage from a non-traumatic cause. The clinical presentation of this condition is nonspecific.

Spontaneous abdominal hemorrhage is defined as the presence of intraabdominal hemorrhage from a nontraumatic and noniatrogenic cause. Common sources of spontaneous abdominal hemorrhage are visceral (hepatic, splenic, renal, and adrenal), gynecologic, coagulopathy-related, and vascular The association between optic disk hemorrhage and glaucoma has been studied for many years. Recently, randomized clinical trials have confirmed that disk hemorrhage is a risk factor for development and progression of glaucoma. Disk hemorrhage is more commonly detected in open-angle glaucoma with normal tension than in open-angle glaucoma with.

Fetal intracranial hemorrhage can be classified on the basis of the anatomic location of the intracranial bleeding. The prognosis is poor in nearly 90% of parenchymal and subdural hemorrhages, whereas it is better in the subgroup with intraventricular hemorrhage. The prognostic scoring system we pro spontaneous abdominal hemorrhage and the CT findings that are essential for prompt diag-nosis and patient management. Appearance of Hemorrhage on CT The appearance of hemorrhage on CT de-pends on its age and location. On unenhanced images, acute bleeding has an attenuation of 30-45 HU because of its high protein con-tent Obstetric hemorrhage is the most common and dangerous complication of childbirth. Traditionally, postpartum hemorrhage (PPH) has been defined as greater than 500 mL estimated blood loss in a vaginal delivery or greater than 1000 mL estimated blood loss at the time of cesarean delivery. This was redefined in 2017 by the American College of.

Diffuse alveolar hemorrhage (DAH) is a life-threatening condition caused by a variety of disorders associated with hemoptysis, anemia, diffuse lung infiltration, and acute respiratory failure. DAH originates from the pulmonary microcirculation, including the alveolar capillaries, arterioles, and venules and is usually diffuse, but may also be. Clinical Management Guidelines for Obstetrician-Gynecologists Background The American College of Obstetricians and Gynecolo-gists' (ACOG) reVITALize program defines postpartum hemorrhage as cumulative blood loss greater than or equal to 1,000 mL or blood loss accompanied by signs or symptoms of hypovolemia within 24 hours after th

Bleeding is usually classified according to clinical or laboratory criteria as major (life-threatening, severe) or minor bleeding (Table 2). 20- 24 However, bleeding that is defined as 'minor' in one study may be classified as 'major' in another; different definitions of bleeding can lead to as much as a three-fold difference in the. Explain long term implications of postpartum hemorrhage such as uterine atony, infertility if hysterectomy is done, or risk of having a postpartum hemorrhage in the future pregnancies. This will give the autonomy to the client to make informed decisions and to begin resolve feelings about current and past events Haemoglobin scavenging in intracranial bleeding: biology and clinical implications Nat Rev Neurol. 2018 Jul;14(7):416-432. doi: 10.1038/s41582-018-0020-. Authors Diederik. Bleeding and thrombosis in critically ill infants and children is a vexing clinical problem. Despite the relatively low incidence of bleeding and thrombosis in the overall pediatric population relative to adults, these critically ill children face unique challenges to hemostasis due to extreme physiologic derangements, exposure of blood to foreign surfaces and membranes, and major vascular. Accumulating evidence advances the critical role of autophagy in brain pathology after stroke. Investigations employing autophagy induction or inhibition using pharmacological tools or autophagy-related gene knockout mice have recently revealed the biological significance of intact and functional au

Hallevi H, Dar NS, Barreto AD, Morales MM, Martin-Schild S, Abraham AT, et al. The IVH score: a novel tool for estimating intraventricular hemorrhage volume: clinical and research implications. Crit Care Med. 2009 Mar. 37(3):969-74, e1. . Kernan WN, Viscoli CM, Brass LM, et al. Phenylpropanolamine and the risk of hemorrhagic stroke Spontaneous Abdominal Hemorrhage: Causes, CT Findings, and Clinical Implications Alessandro Furlan 1 2 , Saeed Fakhran 1 and Michael P. Federle 1 3 Audio Available | Share Claim CM Obstetric hemorrhage is the most common and dangerous complication of childbirth. Traditionally, postpartum hemorrhage (PPH) has been defined as greater than 500 mL estimated blood loss in a vaginal delivery or greater than 1000 mL estimated blood loss at the time of cesarean delivery. This was redefined in 2017 by the American College of Obstetrics and Gynecology as a cumulative blood loss.

Rbcs & its clinical implications

Bleeding, also called hemorrhage, is the name used to describe blood loss. It can refer to blood loss inside the body, called internal bleeding, or to blood loss outside of the body, called. Postpartum hemorrhage is common and can occur in patients without risk factors for hemorrhage. Active management of the third stage of labor should be used routinely to reduce its incidence. Use. author = Brad Zacharia and Santiago Ortega-Gutierrez and Connolly, {E. Sander}

The association between optic disk hemorrhage and glaucoma has been studied for many years. Recently, randomized clinical trials have confirmed that disk hemorrhage is a risk factor for development and progression of glaucoma. Disk hemorrhage is more commonly detected in open-angle glaucoma with normal tension than in open-angle glaucoma with. Cerebral hemorrhage is uncontrolled bleeding in the brain. It can occur from an injury or as a result of a leaky or burst blood vessel. This can happen when a blood vessel gets weakened enough that its wall can no longer withstand the pressure of the blood flowing through it Postpartum hemorrhage can be prevented by various methods: the first being reducing the risk factors for developing anemia, i.e., by ensuring that hemoglobin levels of the mother are greater than. hemorrhage [hem´ŏ-rij] the escape of blood from a ruptured vessel; it can be either external or internal. Blood from an artery is bright red in color and comes in spurts; that from a vein is dark red and comes in a steady flow. Aside from the obvious flow of blood from a wound or body orifice, massive hemorrhage can be detected by other signs, such as.

Clinical presentation and role of CT: • The clinical presentation is usually non-specific; thus frequently the diagnosis is made on the basis of radiologic findings. • CT plays an important role for the assessment of the presence, location and extent of hemorrhage and for the identification of the underlying cause [1-3] Subarachnoid hemorrhage (SAH) is a type of stroke. Head trauma is the most common cause. In patients without head trauma, SAH is most commonly caused by a brain aneurysm. A brain aneurysm is a ballooning of an artery in the brain that can rupture and bleed into the space between the brain and the skull. Risk factors for developing an aneurysm. Hematemesis is the vomiting of blood, which may be obviously red or have an appearance similar to coffee grounds. Melena is the passage of black, tarry stools. Hematochezia is the passage of fresh blood per anus, usually in or with stools Abnormal uterine bleeding (AUB) is a broad term that describes irregularities in the menstrual cycle involving frequency, regularity, duration, and volume of flow outside of pregnancy. Up to one-third of women will experience abnormal uterine bleeding in their life, with irregularities most commonly occurring at menarche and perimenopause. A normal menstrual cycle has a frequency of 24 to 38.

Haemorrhage - SlideShar

  1. Postpartum hemorrhage, the loss of more than 500 mL of blood after delivery, occurs in up to 18 percent of births and is the most common maternal morbidity in developed countries. Although risk.
  2. A brain hemorrhage is a type of stroke. It's caused by an artery in the brain bursting and causing localized bleeding in the surrounding tissues. This bleeding kills brain cells.. The Greek root.
  3. Postpartum hemorrhage (PPH) is commonly defined as blood loss exceeding 500 mL following vaginal birth and 1000 mL following cesarean. Definitions vary, however, and are often based on inaccurate estimates of blood loss. Moreover, average blood loss at birth frequently exceeds 500 or 1000 mL. Proposed alternate metrics for defining and diagnosing PPH include change in hematocrit, need for.
  4. imum blood platelet level before dental sur-gical procedures is approximately 50,000/µL; extensive surgery may require > 100,000/µL..

Obstetric hemorrhage: anesthetic implications - SlideShar

Haemoglobin scavenging in intracranial bleeding: biology and clinical implications. Diederik Bulters 1 na1, Ben Gaastra 1 na1, Ardalan Zolnourian 1, Sheila Alexander 2, Dianxu Ren 2, Spiros L. Laboratory Diagnosis of Bleeding Disorders October 13, 2003 10:00 am 4 COAGULATION CASCADE Va/Xa/PL VIIIa/IXa/PL or VIIa/TF FXII FXIIa TF FVII FG F FXI HMWK FXIa or VIIa/TFVIIa/TF FVIIa FIX Ca+2 FIXa Ca+2 Ca+2 Ca+2 VIII VIIIa Neonatal Clinical Guideline: Critical Bleeding Protocol References and related external legislation, policies, and guidelines 1. Lee SJ, Kim JK, Kim SJ. The clinical characteristics and prognosis of subgaleal hemorrhage in newborn. Korean J Pediatr. 2018 Dec; 61(12):387-391. 2. Assad M, Spaight M, Sink D, Martin J The efficacy of hyperbaric oxygen in hemorrhagic stroke: Experimental and clinical implications. August 2017; Archives of Medical Science 13(5) DOI: (HBOT) for brain hemorrhage has been noted. The clinical presentation of ICH does not differ from acute ischemic stroke, with the sudden onset of a focal neurological deficit. However, certain clinical findings significantly increase the probability of intracranial hemorrhage, such as coma, neck stiffness, seizures accompanying the neurologic deficit, diastolic blood pressure > 110 mmHg, vomiting, and headache

The clinical spectrum of cerebral amyloid angiopathy: presentations without lobar hemorrhage. Neurology 1993; 43:2073. Zerna C, Modi J, Bilston L, et al. Cerebral Microbleeds and Cortical Superficial Siderosis in Patients Presenting With Minor Cerebrovascular Events Postpartum hemorrhage (PPH) is an obstetric emergency. It is one of the top five causes of maternal mortality in both high and low per capita income countries, although the absolute risk of death from PPH is much lower in high-income countries. Timely recognition, appropriate resources, and appropriate response are critical for preventing death A set of clinical and radiological criteria (known as the Boston criteria) have been developed and validated for the diagnosis of probable and possible CAA 29, 30.The following are the radiological manifestations of CAA: lobar ICH, convexal subarachnoid hemorrhage (cSAH), cerebral microbleeds (CMBs), cortical superficial siderosis (cSS), and white matter hyperintensity in posterior brain regions

3 hemorrhage - SlideShar

Vasa previa has been defined as the presence of a fetal vessel or vessels unsupported by either placenta or umbilical cord running in the membranes below the presenting fetal part, either over the cervix 1,2 or in the lower (unquantified) uterus. 3-7 In reviewing the literature in 1999, Oyelese 5 found an overall incidence of 1 in 2,500 births in four major English language series, totaling. Clinical Implications of Intraventricular Hemorrhage Kevin Sheth, MD, reviewing Hallevi H et al. Neurology 2008 Mar 11 Intracerebral hemorrhage volume was linked to presence of intraventricular hemorrhage in this retrospective study The signs and symptoms of subarachnoid hemorrhage (SAH) range from subtle prodromal events to the classic presentation. Prodromal events often are misdiagnosed, while the classic presentation is one of the most pathognomonic pictures in all of clinical medicine

Hemorrhage - SlideShar

Subarachnoid Hemorrhage Complications. A subarachnoid hemorrhage can have serious short- and long-term effects. One potentially fatal problem is that a brain aneurysm will bleed again 1. Introduction. Subarachnoid hemorrhage (SAH) from a ruptured aneurysm is a subtype of stroke that occurs in relatively young patients (median age around 55 years of age) and has high rates of case fatality and morbidity .The most important determinants of poor functional outcome after aneurysmal SAH are early brain injury (EBI) in the first 72 h after the SAH, rebleeding of the aneurysm, and.

Intracranial hemorrhage - SlideShar

Intraparenchymal hemorrhage (IPH; Figure 1) refers to nontraumatic bleeding into the brain parenchyma. (Intracerebral hemorrhage, often abbreviated ICH, is used more often in the clinical literature.) Subarachnoid hemorrhage (SAH) refers to bleeding into the space between the pia and the arachnoid membranes Behboo R, Zanella S, Ruffolo C, Vafai M, Marino F, Scarpa M. Stapled haemorrhoidopexy: extent of tissue excision and clinical implications in the early postoperative period. Colorectal Dis. 2011 Jun. 13(6):697-702. . Pattana-arun J, Wesarachawit W, Tantiphlachiva K, Atithansakul P, Sahakitrungruang C, Rojanasakul A

Postpartum hemorrhage - SlideShar

Postpartum hemorrhage: incidence, risk factors and outcomes in a low-resource setting. Solwayo Ngwenya1-3 1Department of Obstetrics and Gynaecology, Mpilo Central Hospital, Bulawayo, Zimbabwe; 2Royal Women's Clinic, Bulawayo, Zimbabwe; 3Medical School, National University of Science and Technology, Matabeleland, Zimbabwe Background: Primary postpartum hemorrhage (PPH) is defined as blood. Disseminated Intravascular Coagulation. Disseminated intravascular coagulation (DIC) is a life-threatening condition characterized by systemic activation of pathways regulating coagulation, which can lead to fibrin clots that may cause organ failure and the concomitant consumption of platelets and coagulation factors with clinical bleeding Tissue hemorrhage is typically characterized by an acute primary phase 16 and then potentially by secondary hemorrhagic transformation in the subacute phase hours or days later. 17, 18 Deoxyhemoglobin has paramagnetic effects that enable myocardial hemorrhage to be detected using T2‐ and T2*‐weighted CMR (T2* relaxation refers to the decay. OBJECTIVE: Not many large studies have reported the true impact of lower-grade intraventricular hemorrhages in preterm infants. We studied the neurodevelopmental outcomes of extremely preterm infants in relation to the severity of intraventricular hemorrhage. METHODS: A regional cohort study of infants born at 23 to 28 weeks' gestation and admitted to a NICU between 1998 and 2004 Clinical Pharmacology of Ibuprofen . Ibuprofen is supplied as tablets with a potency of 200 to 800 mg.6 The usual dose is 400 to 800 mg three times a day.7 It is almost insoluble in water having pKa of 5.3.8 It is well absorbed orally; peak serum concentrations are attained in 1 to 2 hours after oral administration. It is rapidly bio-transformed with a serum half life of 1.8 to 2 hours

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Signs and symptoms of spontaneous bleeding include: Unexplained and excessive bleeding from cuts or injuries, or after surgery or dental work. Many large or deep bruises. Unusual bleeding after vaccinations. Pain, swelling or tightness in your joints. Blood in your urine or stool. Nosebleeds without a known cause Clinical Features. Any woman presenting with antepartum haemorrhage (APH) should be assessed in a systematic manner (see box below). Placenta praevia classically presents as painless vaginal bleeding, this can vary between spotting to massive haemorrhage.There can be pain if the woman is in labour. Examination may reveal risk factors pertinent to placenta praevia - e.g. c-section scar or. fused myocardial infarction. During the clinical develop- ment of thrombolytic therapy, hemorrhagic myocardial infarction (HMI) was only noted at postmortem examination (1 -6). Its clinical significance remains unclear, because of the lack of reliable methods to iden- tify the presence of intramyocardial hemorrhage in vivo A subarachnoid hemorrhage results from an aneurysmal rupture or traumatic head injury. SAH occurs in the subarachnoid space between the arachnoid membrane and the pia mater that surrounds the brain. 15% of acute strokes are hemorrhagic stroke s which are caused by bursting of a blood vessel i.e. acute hemorrhage While management of patients with deep-seated intracerebral hemorrhage (ICH) is well established, there are scarce data on patients with ICH who require prolonged mechanical ventilation (PMV) during the course of their acute disease. Therefore, we aimed to determine the influence of PMV on mortality in patients with ICH and to identify associated risk factors A controlled clinical trial of cimetidine in the recurrence of variceal hemorrhage: implications about the pathogenesis of hemorrhage. Macdougall BR, Williams R. In a prospective randomized double-blind controlled trial, 51 patients, 16 with cirrhosis and 35 with extrahepatic portal hypertension all of whom presented with variceal bleeding.

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